Gene information
Official symbol TNF
Official full name tumor necrosis factor
Gene type protein-coding gene
Chromosome6p21.33
Alias symbolTNFSF2; DIF; TNF-alpha
Previous symbolTNFA
Gene familyTumor necrosis factor superfamily
Resources
Entrez Gene 7124
HGNC HGNC:11892
Ensembl ENSG00000232810
Vega OTTHUMG00000031194
UCSC uc011fee.4
GO terms: 526 records
GO Description Category LogP Number of genes Detail
GO:0000165 MAPK cascade GO Biological Processes -7.43732657 14 More
GO:0001101 response to acid chemical GO Biological Processes -10.2965313 26 More
GO:0001666 response to hypoxia GO Biological Processes -40.6131384 77 More
GO:0001775 cell activation GO Biological Processes -43.3738118 71 More
GO:0001816 cytokine production GO Biological Processes -9.14810130 8 More
GO:0001818 negative regulation of cytokine production GO Biological Processes -48.9957481 97 More
GO:0001819 positive regulation of cytokine production GO Biological Processes -44.1872667 64 More
GO:0001889 liver development GO Biological Processes -10.3922429 25 More
GO:0001891 phagocytic cup GO Cellular Components -3.03394175 6 More
GO:0001934 positive regulation of protein phosphorylation GO Biological Processes -52.8272623 84 More
GO:0001936 regulation of endothelial cell proliferation GO Biological Processes -54.5504306 75 More
GO:0001937 negative regulation of endothelial cell proliferation GO Biological Processes -27.2173755 21 More
GO:0002020 protease binding GO Molecular Functions -28.8254555 31 More
GO:0002027 regulation of heart rate GO Biological Processes -9.97103962 23 More
GO:0002221 pattern recognition receptor signaling pathway GO Biological Processes -6.97185167 18 More
GO:0002224 toll-like receptor signaling pathway GO Biological Processes -4.97797298 7 More
GO:0002237 response to molecule of bacterial origin GO Biological Processes -48.4964960 93 More
GO:0002274 myeloid leukocyte activation GO Biological Processes -20.6988408 25 More
GO:0002437 inflammatory response to antigenic stimulus GO Biological Processes -7.96781477 8 More
GO:0002520 immune system development GO Biological Processes -15.2957169 80 More
GO:0002521 leukocyte differentiation GO Biological Processes -12.4650129 27 More
GO:0002526 acute inflammatory response GO Biological Processes -34.5980034 29 More
GO:0002544 chronic inflammatory response GO Biological Processes -7.69370672 5 More
GO:0002573 myeloid leukocyte differentiation GO Biological Processes -7.83519790 12 More
GO:0002637 regulation of immunoglobulin production GO Biological Processes -8.47662495 11 More
GO:0002673 regulation of acute inflammatory response GO Biological Processes -15.6954767 14 More
GO:0002675 positive regulation of acute inflammatory response GO Biological Processes -10.8573789 13 More
GO:0002683 negative regulation of immune system process GO Biological Processes -26.6415063 77 More
GO:0002685 regulation of leukocyte migration GO Biological Processes -36.943236 43 More
GO:0002687 positive regulation of leukocyte migration GO Biological Processes -31.0737422 33 More
GO:0002694 regulation of leukocyte activation GO Biological Processes -32.0887020 60 More
GO:0002696 positive regulation of leukocyte activation GO Biological Processes -27.9249645 47 More
GO:0002697 regulation of immune effector process GO Biological Processes -33.2683521 48 More
GO:0002698 negative regulation of immune effector process GO Biological Processes -11.7829906 16 More
GO:0002699 positive regulation of immune effector process GO Biological Processes -18.3926498 29 More
GO:0002700 regulation of production of molecular mediator of immune response GO Biological Processes -19.7615296 26 More
GO:0002701 negative regulation of production of molecular mediator of immune response GO Biological Processes -8.92314992 9 More
GO:0002703 regulation of leukocyte mediated immunity GO Biological Processes -18.0432682 27 More
GO:0002705 positive regulation of leukocyte mediated immunity GO Biological Processes -8.38274670 14 More
GO:0002706 regulation of lymphocyte mediated immunity GO Biological Processes -13.7265777 21 More
GO:0002708 positive regulation of lymphocyte mediated immunity GO Biological Processes -8.31079168 13 More
GO:0002712 regulation of B cell mediated immunity GO Biological Processes -6.15575915 8 More
GO:0002714 positive regulation of B cell mediated immunity GO Biological Processes -6.30679788 7 More
GO:0002718 regulation of cytokine production involved in immune response GO Biological Processes -15.9157324 18 More
GO:0002719 negative regulation of cytokine production involved in immune response GO Biological Processes -9.55471636 12 More
GO:0002761 regulation of myeloid leukocyte differentiation GO Biological Processes -12.4818724 17 More
GO:0002763 positive regulation of myeloid leukocyte differentiation GO Biological Processes -8.56410954 10 More
GO:0002764 immune response-regulating signaling pathway GO Biological Processes -3.80325753 14 More
GO:0002791 regulation of peptide secretion GO Biological Processes -16.5189310 23 More
GO:0002819 regulation of adaptive immune response GO Biological Processes -16.0189388 24 More
GO:0002821 positive regulation of adaptive immune response GO Biological Processes -12.1298033 16 More
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO Biological Processes -14.6775052 22 More
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO Biological Processes -10.1498702 14 More
GO:0002861 regulation of inflammatory response to antigenic stimulus GO Biological Processes -5.72585157 11 More
GO:0002889 regulation of immunoglobulin mediated immune response GO Biological Processes -6.15575915 8 More
GO:0002891 positive regulation of immunoglobulin mediated immune response GO Biological Processes -6.30679788 7 More
GO:0003009 skeletal muscle contraction GO Biological Processes -5.75059946 6 More
GO:0003012 muscle system process GO Biological Processes -27.3938503 63 More
GO:0003013 circulatory system process GO Biological Processes -65.2875605 130 More
GO:0003018 vascular process in circulatory system GO Biological Processes -47.1670528 52 More
GO:0003073 regulation of systemic arterial blood pressure GO Biological Processes -22.2238525 34 More
GO:0003085 negative regulation of systemic arterial blood pressure GO Biological Processes -9.78130162 11 More
GO:0005125 cytokine activity GO Molecular Functions -54.7097150 57 More
GO:0005126 cytokine receptor binding GO Molecular Functions -41.4908940 50 More
GO:0005164 tumor necrosis factor receptor binding GO Molecular Functions -5.56986570 6 More
GO:0005975 carbohydrate metabolic process GO Biological Processes -4.30473825 38 More
GO:0005996 monosaccharide metabolic process GO Biological Processes -2.87918856 8 More
GO:0006006 glucose metabolic process GO Biological Processes -4.31450208 8 More
GO:0006417 regulation of translation GO Biological Processes -24.5257987 35 More
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -5.45408545 14 More
GO:0006936 muscle contraction GO Biological Processes -17.3443769 27 More
GO:0006941 striated muscle contraction GO Biological Processes -9.86033061 14 More
GO:0006954 inflammatory response GO Biological Processes -86.5569367 100 More
GO:0006959 humoral immune response GO Biological Processes -20.5068158 33 More
GO:0006970 response to osmotic stress GO Biological Processes -4.47323224 7 More
GO:0006974 cellular response to DNA damage stimulus GO Biological Processes -1.56334957 15 More
GO:0007159 leukocyte cell-cell adhesion GO Biological Processes -16.8529519 16 More
GO:0007346 regulation of mitotic cell cycle GO Biological Processes -10.6017433 22 More
GO:0007623 circadian rhythm GO Biological Processes -8.17635164 13 More
GO:0008015 blood circulation GO Biological Processes -65.7270163 119 More
GO:0008016 regulation of heart contraction GO Biological Processes -27.6827716 55 More
GO:0008217 regulation of blood pressure GO Biological Processes -35.2019435 60 More
GO:0008283 cell population proliferation GO Biological Processes -17.2298624 68 More
GO:0008285 negative regulation of cell population proliferation GO Biological Processes -53.5569125 147 More
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage GO Biological Processes -5.52642112 8 More
GO:0009314 response to radiation GO Biological Processes -9.77450393 26 More
GO:0009410 response to xenobiotic stimulus GO Biological Processes -32.6021211 82 More
GO:0009581 detection of external stimulus GO Biological Processes -2.05740021 12 More
GO:0009582 detection of abiotic stimulus GO Biological Processes -2.39356289 13 More
GO:0009612 response to mechanical stimulus GO Biological Processes -18.7627330 44 More
GO:0009615 response to virus GO Biological Processes -11.2861143 47 More
GO:0009617 response to bacterium GO Biological Processes -52.1760880 83 More
GO:0009636 response to toxic substance GO Biological Processes -18.1818984 46 More
GO:0009651 response to salt stress GO Biological Processes -4.88843929 5 More
GO:0009725 response to hormone GO Biological Processes -49.1091700 138 More
GO:0009895 negative regulation of catabolic process GO Biological Processes -10.3621088 43 More
GO:0009896 positive regulation of catabolic process GO Biological Processes -13.5088608 63 More
GO:0009897 external side of plasma membrane GO Cellular Components -28.0033937 46 More
GO:0009991 response to extracellular stimulus GO Biological Processes -42.2178323 102 More
GO:0010001 glial cell differentiation GO Biological Processes -13.0211768 33 More
GO:0010466 negative regulation of peptidase activity GO Biological Processes -24.1438543 35 More
GO:0010469 regulation of signaling receptor activity GO Biological Processes -13.5880476 20 More
GO:0010563 negative regulation of phosphorus metabolic process GO Biological Processes -21.7837721 71 More
GO:0010564 regulation of cell cycle process GO Biological Processes -6.45429517 20 More
GO:0010573 vascular endothelial growth factor production GO Biological Processes -10.4763648 6 More
GO:0010594 regulation of endothelial cell migration GO Biological Processes -41.8778170 72 More
GO:0010596 negative regulation of endothelial cell migration GO Biological Processes -31.4991544 25 More
GO:0010632 regulation of epithelial cell migration GO Biological Processes -42.8870194 81 More
GO:0010633 negative regulation of epithelial cell migration GO Biological Processes -29.7632977 25 More
GO:0010638 positive regulation of organelle organization GO Biological Processes -6.49207636 47 More
GO:0010720 positive regulation of cell development GO Biological Processes -17.713649 52 More
GO:0010721 negative regulation of cell development GO Biological Processes -6.74707916 25 More
GO:0010817 regulation of hormone levels GO Biological Processes -29.5190556 49 More
GO:0010827 regulation of glucose transmembrane transport GO Biological Processes -18.4601079 28 More
GO:0010829 negative regulation of glucose transmembrane transport GO Biological Processes -8.17037988 10 More
GO:0010876 lipid localization GO Biological Processes -20.1994935 34 More
GO:0010883 regulation of lipid storage GO Biological Processes -22.5241589 19 More
GO:0010888 negative regulation of lipid storage GO Biological Processes -13.5596033 10 More
GO:0010893 positive regulation of steroid biosynthetic process GO Biological Processes -3.84190664 4 More
GO:0010942 positive regulation of cell death GO Biological Processes -48.7037743 123 More
GO:0010950 positive regulation of endopeptidase activity GO Biological Processes -13.2452311 34 More
GO:0010951 negative regulation of endopeptidase activity GO Biological Processes -24.7873219 35 More
GO:0010952 positive regulation of peptidase activity GO Biological Processes -14.1524623 37 More
GO:0010958 regulation of amino acid import across plasma membrane GO Biological Processes -6.20743023 5 More
GO:0014013 regulation of gliogenesis GO Biological Processes -13.3514185 26 More
GO:0014015 positive regulation of gliogenesis GO Biological Processes -11.0528361 19 More
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling GO Biological Processes -15.9250248 30 More
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling GO Biological Processes -18.2876323 28 More
GO:0014823 response to activity GO Biological Processes -19.5783025 27 More
GO:0016525 negative regulation of angiogenesis GO Biological Processes -31.9326641 51 More
GO:0019216 regulation of lipid metabolic process GO Biological Processes -24.8423986 38 More
GO:0019218 regulation of steroid metabolic process GO Biological Processes -14.2494824 17 More
GO:0019221 cytokine-mediated signaling pathway GO Biological Processes -27.5840932 43 More
GO:0019233 sensory perception of pain GO Biological Processes -10.7642352 20 More
GO:0019318 hexose metabolic process GO Biological Processes -3.25353717 8 More
GO:0019722 calcium-mediated signaling GO Biological Processes -11.6647584 29 More
GO:0019932 second-messenger-mediated signaling GO Biological Processes -19.1717114 46 More
GO:0021782 glial cell development GO Biological Processes -9.97103962 23 More
GO:0022407 regulation of cell-cell adhesion GO Biological Processes -32.4337382 53 More
GO:0022409 positive regulation of cell-cell adhesion GO Biological Processes -25.7751074 39 More
GO:0022612 gland morphogenesis GO Biological Processes -7.35048069 19 More
GO:0030029 actin filament-based process GO Biological Processes -9.62516039 61 More
GO:0030036 actin cytoskeleton organization GO Biological Processes -5.67075265 47 More
GO:0030097 hemopoiesis GO Biological Processes -14.1443585 71 More
GO:0030099 myeloid cell differentiation GO Biological Processes -6.71806250 15 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030162 regulation of proteolysis GO Biological Processes -41.2267045 73 More
GO:0030198 extracellular matrix organization GO Biological Processes -21.4880730 33 More
GO:0030316 osteoclast differentiation GO Biological Processes -2.15842877 6 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0030336 negative regulation of cell migration GO Biological Processes -30.9008082 37 More
GO:0030545 signaling receptor regulator activity GO Molecular Functions -87.4728446 102 More
GO:0030546 signaling receptor activator activity GO Molecular Functions -90.4065983 101 More
GO:0030856 regulation of epithelial cell differentiation GO Biological Processes -15.4645914 35 More
GO:0031099 regeneration GO Biological Processes -17.4553316 23 More
GO:0031100 animal organ regeneration GO Biological Processes -17.1438387 17 More
GO:0031331 positive regulation of cellular catabolic process GO Biological Processes -13.5134767 30 More
GO:0031334 positive regulation of protein-containing complex assembly GO Biological Processes -8.84926570 16 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031349 positive regulation of defense response GO Biological Processes -32.1301903 71 More
GO:0031400 negative regulation of protein modification process GO Biological Processes -17.0986645 70 More
GO:0031641 regulation of myelination GO Biological Processes -3.81944625 9 More
GO:0031644 regulation of nervous system process GO Biological Processes -8.22607591 24 More
GO:0031667 response to nutrient levels GO Biological Processes -41.8130555 98 More
GO:0031960 response to corticosteroid GO Biological Processes -20.1789519 26 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0032496 response to lipopolysaccharide GO Biological Processes -45.257773 87 More
GO:0032526 response to retinoic acid GO Biological Processes -5.75287026 10 More
GO:0032642 regulation of chemokine production GO Biological Processes -25.2850711 37 More
GO:0032649 regulation of interferon-gamma production GO Biological Processes -12.4733429 27 More
GO:0032651 regulation of interleukin-1 beta production GO Biological Processes -19.7300517 34 More
GO:0032652 regulation of interleukin-1 production GO Biological Processes -24.2088254 41 More
GO:0032661 regulation of interleukin-18 production GO Biological Processes -4.01518900 3 More
GO:0032675 regulation of interleukin-6 production GO Biological Processes -28.2553997 51 More
GO:0032677 regulation of interleukin-8 production GO Biological Processes -20.0046302 33 More
GO:0032715 negative regulation of interleukin-6 production GO Biological Processes -14.4703936 13 More
GO:0032722 positive regulation of chemokine production GO Biological Processes -22.4503100 21 More
GO:0032729 positive regulation of interferon-gamma production GO Biological Processes -7.58110530 10 More
GO:0032731 positive regulation of interleukin-1 beta production GO Biological Processes -11.8061175 13 More
GO:0032732 positive regulation of interleukin-1 production GO Biological Processes -14.7376831 16 More
GO:0032755 positive regulation of interleukin-6 production GO Biological Processes -18.6559032 31 More
GO:0032757 positive regulation of interleukin-8 production GO Biological Processes -14.6396218 15 More
GO:0032768 regulation of monooxygenase activity GO Biological Processes -14.2762890 21 More
GO:0032770 positive regulation of monooxygenase activity GO Biological Processes -9.70418585 13 More
GO:0032813 tumor necrosis factor receptor superfamily binding GO Molecular Functions -5.47819787 7 More
GO:0032872 regulation of stress-activated MAPK cascade GO Biological Processes -11.6818048 20 More
GO:0032874 positive regulation of stress-activated MAPK cascade GO Biological Processes -9.63549885 15 More
GO:0032890 regulation of organic acid transport GO Biological Processes -14.1608908 23 More
GO:0032891 negative regulation of organic acid transport GO Biological Processes -5.29413319 5 More
GO:0033135 regulation of peptidyl-serine phosphorylation GO Biological Processes -8.68560410 14 More
GO:0033138 positive regulation of peptidyl-serine phosphorylation GO Biological Processes -6.77396219 11 More
GO:0033209 tumor necrosis factor-mediated signaling pathway GO Biological Processes -6.18341292 8 More
GO:0033674 positive regulation of kinase activity GO Biological Processes -29.8538991 87 More
GO:0034114 regulation of heterotypic cell-cell adhesion GO Biological Processes -12.8696023 10 More
GO:0034248 regulation of cellular amide metabolic process GO Biological Processes -28.1662419 40 More
GO:0034250 positive regulation of cellular amide metabolic process GO Biological Processes -3.04911747 8 More
GO:0034341 response to interferon-gamma GO Biological Processes -10.8524889 26 More
GO:0034612 response to tumor necrosis factor GO Biological Processes -24.4651326 32 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034763 negative regulation of transmembrane transport GO Biological Processes -22.14661 42 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0034766 negative regulation of ion transmembrane transport GO Biological Processes -15.824921 16 More
GO:0035094 response to nicotine GO Biological Processes -8.07167727 14 More
GO:0035150 regulation of tube size GO Biological Processes -44.5138102 41 More
GO:0035296 regulation of tube diameter GO Biological Processes -44.6572858 41 More
GO:0035305 negative regulation of dephosphorylation GO Biological Processes -2.31313807 3 More
GO:0036293 response to decreased oxygen levels GO Biological Processes -40.9544531 79 More
GO:0040013 negative regulation of locomotion GO Biological Processes -30.7871461 81 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0042063 gliogenesis GO Biological Processes -20.3412228 47 More
GO:0042116 macrophage activation GO Biological Processes -15.3664951 15 More
GO:0042176 regulation of protein catabolic process GO Biological Processes -8.45353494 23 More
GO:0042391 regulation of membrane potential GO Biological Processes -15.0641346 59 More
GO:0042509 regulation of tyrosine phosphorylation of STAT protein GO Biological Processes -19.4049069 20 More
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein GO Biological Processes -19.8380655 19 More
GO:0042634 regulation of hair cycle GO Biological Processes -2.36203981 3 More
GO:0042742 defense response to bacterium GO Biological Processes -25.9215771 41 More
GO:0043025 neuronal cell body GO Cellular Components -9.18558636 52 More
GO:0043062 extracellular structure organization GO Biological Processes -21.4370160 33 More
GO:0043065 positive regulation of apoptotic process GO Biological Processes -46.1285536 112 More
GO:0043068 positive regulation of programmed cell death GO Biological Processes -46.5713594 114 More
GO:0043086 negative regulation of catalytic activity GO Biological Processes -41.1437610 130 More
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling GO Biological Processes -8.71585030 18 More
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling GO Biological Processes -8.04470175 15 More
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -5.11653120 8 More
GO:0043200 response to amino acid GO Biological Processes -9.16129691 23 More
GO:0043243 positive regulation of protein-containing complex disassembly GO Biological Processes -3.26415888 7 More
GO:0043244 regulation of protein-containing complex disassembly GO Biological Processes -2.18901367 12 More
GO:0043254 regulation of protein-containing complex assembly GO Biological Processes -7.63830100 21 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043271 negative regulation of ion transport GO Biological Processes -19.3914052 40 More
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -11.0338596 16 More
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -14.7594418 39 More
GO:0043405 regulation of MAP kinase activity GO Biological Processes -18.9267681 42 More
GO:0043406 positive regulation of MAP kinase activity GO Biological Processes -13.8261343 18 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0043457 regulation of cellular respiration GO Biological Processes -4.43542328 10 More
GO:0043467 regulation of generation of precursor metabolites and energy GO Biological Processes -10.8295915 27 More
GO:0043491 protein kinase B signaling GO Biological Processes -12.2973970 11 More
GO:0043523 regulation of neuron apoptotic process GO Biological Processes -14.5388618 39 More
GO:0043525 positive regulation of neuron apoptotic process GO Biological Processes -3.54364153 9 More
GO:0043535 regulation of blood vessel endothelial cell migration GO Biological Processes -45.8916712 37 More
GO:0043537 negative regulation of blood vessel endothelial cell migration GO Biological Processes -32.3610392 24 More
GO:0043549 regulation of kinase activity GO Biological Processes -36.8507249 123 More
GO:0044057 regulation of system process GO Biological Processes -61.6610386 136 More
GO:0044070 regulation of anion transport GO Biological Processes -12.6410846 24 More
GO:0044089 positive regulation of cellular component biogenesis GO Biological Processes -10.7794496 56 More
GO:0044297 cell body GO Cellular Components -11.7206640 62 More
GO:0045069 regulation of viral genome replication GO Biological Processes -1.96545001 9 More
GO:0045121 membrane raft GO Cellular Components -30.0775030 71 More
GO:0045123 cellular extravasation GO Biological Processes -12.7826256 12 More
GO:0045229 external encapsulating structure organization GO Biological Processes -21.3355594 33 More
GO:0045321 leukocyte activation GO Biological Processes -25.4958219 48 More
GO:0045428 regulation of nitric oxide biosynthetic process GO Biological Processes -19.2075726 26 More
GO:0045429 positive regulation of nitric oxide biosynthetic process GO Biological Processes -13.6962150 18 More
GO:0045471 response to ethanol GO Biological Processes -15.9991788 20 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0045598 regulation of fat cell differentiation GO Biological Processes -17.6607153 22 More
GO:0045599 negative regulation of fat cell differentiation GO Biological Processes -10.0272645 11 More
GO:0045601 regulation of endothelial cell differentiation GO Biological Processes -11.5275821 17 More
GO:0045637 regulation of myeloid cell differentiation GO Biological Processes -9.39364926 18 More
GO:0045639 positive regulation of myeloid cell differentiation GO Biological Processes -7.07849207 11 More
GO:0045667 regulation of osteoblast differentiation GO Biological Processes -10.7517956 27 More
GO:0045668 negative regulation of osteoblast differentiation GO Biological Processes -3.60984508 9 More
GO:0045670 regulation of osteoclast differentiation GO Biological Processes -10.2566667 12 More
GO:0045672 positive regulation of osteoclast differentiation GO Biological Processes -7.61299657 7 More
GO:0045732 positive regulation of protein catabolic process GO Biological Processes -6.83749864 15 More
GO:0045765 regulation of angiogenesis GO Biological Processes -63.6171248 109 More
GO:0045776 negative regulation of blood pressure GO Biological Processes -17.1357953 22 More
GO:0045785 positive regulation of cell adhesion GO Biological Processes -29.6368249 50 More
GO:0045786 negative regulation of cell cycle GO Biological Processes -11.4279863 20 More
GO:0045787 positive regulation of cell cycle GO Biological Processes -4.54703082 15 More
GO:0045822 negative regulation of heart contraction GO Biological Processes -5.99274362 5 More
GO:0045833 negative regulation of lipid metabolic process GO Biological Processes -7.94928400 20 More
GO:0045834 positive regulation of lipid metabolic process GO Biological Processes -24.1838255 28 More
GO:0045859 regulation of protein kinase activity GO Biological Processes -34.3615088 109 More
GO:0045860 positive regulation of protein kinase activity GO Biological Processes -29.3929160 47 More
GO:0045861 negative regulation of proteolysis GO Biological Processes -27.9905009 43 More
GO:0045862 positive regulation of proteolysis GO Biological Processes -17.3242033 33 More
GO:0045930 negative regulation of mitotic cell cycle GO Biological Processes -12.1211141 17 More
GO:0045936 negative regulation of phosphate metabolic process GO Biological Processes -21.8424865 71 More
GO:0045940 positive regulation of steroid metabolic process GO Biological Processes -11.4541194 10 More
GO:0046324 regulation of glucose import GO Biological Processes -14.8736114 22 More
GO:0046325 negative regulation of glucose import GO Biological Processes -8.14754197 9 More
GO:0046328 regulation of JNK cascade GO Biological Processes -6.26985667 21 More
GO:0046330 positive regulation of JNK cascade GO Biological Processes -6.26494407 10 More
GO:0046425 regulation of receptor signaling pathway via JAK-STAT GO Biological Processes -10.5317026 20 More
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT GO Biological Processes -10.8890337 15 More
GO:0046883 regulation of hormone secretion GO Biological Processes -20.4338227 29 More
GO:0046889 positive regulation of lipid biosynthetic process GO Biological Processes -14.1380112 16 More
GO:0046890 regulation of lipid biosynthetic process GO Biological Processes -16.6841590 23 More
GO:0048018 receptor ligand activity GO Molecular Functions -91.0736151 101 More
GO:0048511 rhythmic process GO Biological Processes -10.3377021 38 More
GO:0048525 negative regulation of viral process GO Biological Processes -2.82207312 11 More
GO:0048534 hematopoietic or lymphoid organ development GO Biological Processes -16.4041704 79 More
GO:0048545 response to steroid hormone GO Biological Processes -20.1914989 32 More
GO:0048565 digestive tract development GO Biological Processes -11.5666667 27 More
GO:0048566 embryonic digestive tract development GO Biological Processes -4.28720299 8 More
GO:0048568 embryonic organ development GO Biological Processes -17.1204114 64 More
GO:0048660 regulation of smooth muscle cell proliferation GO Biological Processes -48.6624498 69 More
GO:0048661 positive regulation of smooth muscle cell proliferation GO Biological Processes -29.0732096 40 More
GO:0048732 gland development GO Biological Processes -26.3979320 74 More
GO:0050673 epithelial cell proliferation GO Biological Processes -5.54644403 9 More
GO:0050678 regulation of epithelial cell proliferation GO Biological Processes -51.9930445 102 More
GO:0050679 positive regulation of epithelial cell proliferation GO Biological Processes -31.4834672 59 More
GO:0050680 negative regulation of epithelial cell proliferation GO Biological Processes -26.5961536 48 More
GO:0050708 regulation of protein secretion GO Biological Processes -30.3716714 63 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0050729 positive regulation of inflammatory response GO Biological Processes -38.1621935 57 More
GO:0050730 regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.1120967 60 More
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.9747849 34 More
GO:0050764 regulation of phagocytosis GO Biological Processes -16.0793009 29 More
GO:0050767 regulation of neurogenesis GO Biological Processes -15.7439029 55 More
GO:0050768 negative regulation of neurogenesis GO Biological Processes -6.01402466 11 More
GO:0050769 positive regulation of neurogenesis GO Biological Processes -12.1167088 37 More
GO:0050778 positive regulation of immune response GO Biological Processes -17.2528761 40 More
GO:0050792 regulation of viral process GO Biological Processes -4.90676471 20 More
GO:0050796 regulation of insulin secretion GO Biological Processes -13.8348879 19 More
GO:0050803 regulation of synapse structure or activity GO Biological Processes -6.38009123 27 More
GO:0050804 modulation of chemical synaptic transmission GO Biological Processes -15.2260557 60 More
GO:0050806 positive regulation of synaptic transmission GO Biological Processes -4.32260958 18 More
GO:0050807 regulation of synapse organization GO Biological Processes -6.08931613 26 More
GO:0050810 regulation of steroid biosynthetic process GO Biological Processes -7.92957130 10 More
GO:0050830 defense response to Gram-positive bacterium GO Biological Processes -13.1972375 17 More
GO:0050865 regulation of cell activation GO Biological Processes -40.6877761 71 More
GO:0050867 positive regulation of cell activation GO Biological Processes -31.2431659 51 More
GO:0050879 multicellular organismal movement GO Biological Processes -5.9470076 7 More
GO:0050881 musculoskeletal movement GO Biological Processes -5.9470076 7 More
GO:0050890 cognition GO Biological Processes -8.00500082 37 More
GO:0050900 leukocyte migration GO Biological Processes -39.9164759 46 More
GO:0050905 neuromuscular process GO Biological Processes -4.83415709 10 More
GO:0050954 sensory perception of mechanical stimulus GO Biological Processes -4.15913068 20 More
GO:0050982 detection of mechanical stimulus GO Biological Processes -3.60984508 9 More
GO:0050994 regulation of lipid catabolic process GO Biological Processes -9.86212956 11 More
GO:0050999 regulation of nitric-oxide synthase activity GO Biological Processes -9.05830591 14 More
GO:0051043 regulation of membrane protein ectodomain proteolysis GO Biological Processes -16.3022563 12 More
GO:0051044 positive regulation of membrane protein ectodomain proteolysis GO Biological Processes -9.19233133 7 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051048 negative regulation of secretion GO Biological Processes -20.2278199 42 More
GO:0051051 negative regulation of transport GO Biological Processes -46.8709407 107 More
GO:0051052 regulation of DNA metabolic process GO Biological Processes -4.01973325 42 More
GO:0051054 positive regulation of DNA metabolic process GO Biological Processes -3.76901955 13 More
GO:0051090 regulation of DNA-binding transcription factor activity GO Biological Processes -25.8933515 78 More
GO:0051091 positive regulation of DNA-binding transcription factor activity GO Biological Processes -17.7436786 49 More
GO:0051092 positive regulation of NF-kappaB transcription factor activity GO Biological Processes -14.8614421 21 More
GO:0051129 negative regulation of cellular component organization GO Biological Processes -13.1016989 75 More
GO:0051222 positive regulation of protein transport GO Biological Processes -13.8994291 46 More
GO:0051223 regulation of protein transport GO Biological Processes -25.2801266 81 More
GO:0051235 maintenance of location GO Biological Processes -6.64896142 13 More
GO:0051271 negative regulation of cellular component movement GO Biological Processes -29.9238399 37 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0051341 regulation of oxidoreductase activity GO Biological Processes -18.1249013 32 More
GO:0051345 positive regulation of hydrolase activity GO Biological Processes -19.7369783 79 More
GO:0051346 negative regulation of hydrolase activity GO Biological Processes -26.0030636 42 More
GO:0051347 positive regulation of transferase activity GO Biological Processes -26.6059528 90 More
GO:0051353 positive regulation of oxidoreductase activity GO Biological Processes -12.6682372 20 More
GO:0051384 response to glucocorticoid GO Biological Processes -16.9609899 22 More
GO:0051606 detection of stimulus GO Biological Processes -2.56190637 17 More
GO:0051785 positive regulation of nuclear division GO Biological Processes -3.17098953 5 More
GO:0051896 regulation of protein kinase B signaling GO Biological Processes -30.5149255 55 More
GO:0051897 positive regulation of protein kinase B signaling GO Biological Processes -23.7578366 39 More
GO:0051952 regulation of amine transport GO Biological Processes -10.5179624 22 More
GO:0051955 regulation of amino acid transport GO Biological Processes -5.24816080 10 More
GO:0051960 regulation of nervous system development GO Biological Processes -17.2202851 64 More
GO:0051961 negative regulation of nervous system development GO Biological Processes -6.75305746 12 More
GO:0051962 positive regulation of nervous system development GO Biological Processes -13.2580156 43 More
GO:0051966 regulation of synaptic transmission, glutamatergic GO Biological Processes -5.51577792 8 More
GO:0052547 regulation of peptidase activity GO Biological Processes -35.5643317 55 More
GO:0052548 regulation of endopeptidase activity GO Biological Processes -34.9486589 53 More
GO:0055123 digestive system development GO Biological Processes -12.1524002 29 More
GO:0060147 regulation of post-transcriptional gene silencing GO Biological Processes -6.75865733 12 More
GO:0060149 negative regulation of post-transcriptional gene silencing GO Biological Processes -7.60090654 9 More
GO:0060251 regulation of glial cell proliferation GO Biological Processes -8.90876897 12 More
GO:0060252 positive regulation of glial cell proliferation GO Biological Processes -5.51502780 7 More
GO:0060284 regulation of cell development GO Biological Processes -22.9455891 78 More
GO:0060341 regulation of cellular localization GO Biological Processes -10.5933083 72 More
GO:0060558 regulation of calcidiol 1-monooxygenase activity GO Biological Processes -8.3287979 5 More
GO:0060627 regulation of vesicle-mediated transport GO Biological Processes -25.1756709 46 More
GO:0060688 regulation of morphogenesis of a branching structure GO Biological Processes -6.83160707 8 More
GO:0060964 regulation of miRNA-mediated gene silencing GO Biological Processes -7.13447853 12 More
GO:0060965 negative regulation of miRNA-mediated gene silencing GO Biological Processes -7.86308931 9 More
GO:0060966 regulation of gene silencing by RNA GO Biological Processes -6.64085561 12 More
GO:0060967 negative regulation of gene silencing by RNA GO Biological Processes -7.60090654 9 More
GO:0061008 hepaticobiliary system development GO Biological Processes -10.9353398 26 More
GO:0061041 regulation of wound healing GO Biological Processes -35.8633788 36 More
GO:0061043 regulation of vascular wound healing GO Biological Processes -4.91299256 6 More
GO:0061045 negative regulation of wound healing GO Biological Processes -28.2986689 25 More
GO:0061756 leukocyte adhesion to vascular endothelial cell GO Biological Processes -8.18952769 7 More
GO:0062012 regulation of small molecule metabolic process GO Biological Processes -26.8746473 69 More
GO:0062013 positive regulation of small molecule metabolic process GO Biological Processes -17.9792910 37 More
GO:0062149 detection of stimulus involved in sensory perception of pain GO Biological Processes -4.25041921 7 More
GO:0070201 regulation of establishment of protein localization GO Biological Processes -24.4831554 82 More
GO:0070265 necrotic cell death GO Biological Processes -3.33685104 4 More
GO:0070266 necroptotic process GO Biological Processes -3.92689699 4 More
GO:0070302 regulation of stress-activated protein kinase signaling cascade GO Biological Processes -11.5600448 20 More
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade GO Biological Processes -9.54226030 15 More
GO:0070372 regulation of ERK1 and ERK2 cascade GO Biological Processes -38.4320790 79 More
GO:0070374 positive regulation of ERK1 and ERK2 cascade GO Biological Processes -34.9831828 64 More
GO:0070482 response to oxygen levels GO Biological Processes -40.7566635 82 More
GO:0070920 regulation of production of small RNA involved in gene silencing by RNA GO Biological Processes -5.08699974 5 More
GO:0071216 cellular response to biotic stimulus GO Biological Processes -28.1549742 59 More
GO:0071219 cellular response to molecule of bacterial origin GO Biological Processes -28.3848077 56 More
GO:0071222 cellular response to lipopolysaccharide GO Biological Processes -26.0381191 52 More
GO:0071229 cellular response to acid chemical GO Biological Processes -7.57719972 18 More
GO:0071230 cellular response to amino acid stimulus GO Biological Processes -6.04975320 15 More
GO:0071300 cellular response to retinoic acid GO Biological Processes -4.69230219 12 More
GO:0071345 cellular response to cytokine stimulus GO Biological Processes -39.647808 70 More
GO:0071346 cellular response to interferon-gamma GO Biological Processes -8.94844866 13 More
GO:0071356 cellular response to tumor necrosis factor GO Biological Processes -22.5666334 29 More
GO:0071396 cellular response to lipid GO Biological Processes -37.0669488 98 More
GO:0071407 cellular response to organic cyclic compound GO Biological Processes -19.6857751 39 More
GO:0071417 cellular response to organonitrogen compound GO Biological Processes -26.3253267 90 More
GO:0071675 regulation of mononuclear cell migration GO Biological Processes -19.9332328 23 More
GO:0071677 positive regulation of mononuclear cell migration GO Biological Processes -15.5919825 16 More
GO:0071900 regulation of protein serine/threonine kinase activity GO Biological Processes -19.5794055 63 More
GO:0071902 positive regulation of protein serine/threonine kinase activity GO Biological Processes -13.5008002 23 More
GO:0072577 endothelial cell apoptotic process GO Biological Processes -3.92643717 3 More
GO:0080135 regulation of cellular response to stress GO Biological Processes -19.0128542 89 More
GO:0080164 regulation of nitric oxide metabolic process GO Biological Processes -19.7892071 27 More
GO:0090066 regulation of anatomical structure size GO Biological Processes -32.7608623 52 More
GO:0090068 positive regulation of cell cycle process GO Biological Processes -2.40180572 9 More
GO:0090087 regulation of peptide transport GO Biological Processes -16.3568662 23 More
GO:0090276 regulation of peptide hormone secretion GO Biological Processes -16.6841590 23 More
GO:0097190 apoptotic signaling pathway GO Biological Processes -11.7839485 23 More
GO:0097191 extrinsic apoptotic signaling pathway GO Biological Processes -9.74858067 13 More
GO:0097193 intrinsic apoptotic signaling pathway GO Biological Processes -4.54525889 10 More
GO:0097237 cellular response to toxic substance GO Biological Processes -13.7473733 28 More
GO:0097300 programmed necrotic cell death GO Biological Processes -3.53254248 4 More
GO:0097305 response to alcohol GO Biological Processes -17.4096682 46 More
GO:0097421 liver regeneration GO Biological Processes -7.12111476 7 More
GO:0097527 necroptotic signaling pathway GO Biological Processes -3.92643717 3 More
GO:0097746 blood vessel diameter maintenance GO Biological Processes -44.6572858 41 More
GO:0098552 side of membrane GO Cellular Components -22.4625650 48 More
GO:0098609 cell-cell adhesion GO Biological Processes -15.7963965 69 More
GO:0098857 membrane microdomain GO Cellular Components -30.8181788 72 More
GO:0098900 regulation of action potential GO Biological Processes -5.92071483 13 More
GO:0099177 regulation of trans-synaptic signaling GO Biological Processes -15.1793607 60 More
GO:0150077 regulation of neuroinflammatory response GO Biological Processes -14.4671881 13 More
GO:0150078 positive regulation of neuroinflammatory response GO Biological Processes -8.75781093 7 More
GO:1900015 regulation of cytokine production involved in inflammatory response GO Biological Processes -18.8349263 16 More
GO:1900017 positive regulation of cytokine production involved in inflammatory response GO Biological Processes -9.17938755 7 More
GO:1900368 regulation of post-transcriptional gene silencing by RNA GO Biological Processes -6.88005887 12 More
GO:1900369 negative regulation of post-transcriptional gene silencing by RNA GO Biological Processes -7.60090654 9 More
GO:1900407 regulation of cellular response to oxidative stress GO Biological Processes -21.4526227 33 More
GO:1901214 regulation of neuron death GO Biological Processes -23.5458880 37 More
GO:1901216 positive regulation of neuron death GO Biological Processes -5.62852599 9 More
GO:1901222 regulation of NIK/NF-kappaB signaling GO Biological Processes -7.00394995 9 More
GO:1901342 regulation of vasculature development GO Biological Processes -64.8504074 111 More
GO:1901343 negative regulation of vasculature development GO Biological Processes -32.5354692 52 More
GO:1901550 regulation of endothelial cell development GO Biological Processes -5.90191637 5 More
GO:1901652 response to peptide GO Biological Processes -34.9047734 89 More
GO:1901653 cellular response to peptide GO Biological Processes -21.5212108 58 More
GO:1901699 cellular response to nitrogen compound GO Biological Processes -26.9091664 96 More
GO:1901888 regulation of cell junction assembly GO Biological Processes -8.71146171 30 More
GO:1901889 negative regulation of cell junction assembly GO Biological Processes -5.33337113 9 More
GO:1902004 positive regulation of amyloid-beta formation GO Biological Processes -2.79007403 3 More
GO:1902105 regulation of leukocyte differentiation GO Biological Processes -18.8286876 32 More
GO:1902107 positive regulation of leukocyte differentiation GO Biological Processes -14.6775052 22 More
GO:1902882 regulation of response to oxidative stress GO Biological Processes -20.0046302 33 More
GO:1902893 regulation of miRNA transcription GO Biological Processes -10.5909336 18 More
GO:1902895 positive regulation of miRNA transcription GO Biological Processes -9.50703189 15 More
GO:1902993 positive regulation of amyloid precursor protein catabolic process GO Biological Processes -3.69512980 4 More
GO:1903034 regulation of response to wounding GO Biological Processes -34.9293555 38 More
GO:1903035 negative regulation of response to wounding GO Biological Processes -27.3379640 26 More
GO:1903037 regulation of leukocyte cell-cell adhesion GO Biological Processes -23.2079690 66 More
GO:1903039 positive regulation of leukocyte cell-cell adhesion GO Biological Processes -20.7355312 32 More
GO:1903076 regulation of protein localization to plasma membrane GO Biological Processes -2.83846671 6 More
GO:1903078 positive regulation of protein localization to plasma membrane GO Biological Processes -2.45650021 8 More
GO:1903140 regulation of establishment of endothelial barrier GO Biological Processes -5.90191637 5 More
GO:1903201 regulation of oxidative stress-induced cell death GO Biological Processes -18.4601079 28 More
GO:1903203 regulation of oxidative stress-induced neuron death GO Biological Processes -4.46557398 5 More
GO:1903209 positive regulation of oxidative stress-induced cell death GO Biological Processes -4.95585983 4 More
GO:1903522 regulation of blood circulation GO Biological Processes -44.9821911 79 More
GO:1903523 negative regulation of blood circulation GO Biological Processes -5.90631959 5 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1903578 regulation of ATP metabolic process GO Biological Processes -8.20286273 19 More
GO:1903579 negative regulation of ATP metabolic process GO Biological Processes -4.61361828 8 More
GO:1903706 regulation of hemopoiesis GO Biological Processes -16.2759166 33 More
GO:1903708 positive regulation of hemopoiesis GO Biological Processes -14.6775052 22 More
GO:1903715 regulation of aerobic respiration GO Biological Processes -2.64333175 6 More
GO:1903789 regulation of amino acid transmembrane transport GO Biological Processes -6.20743023 5 More
GO:1903792 negative regulation of anion transport GO Biological Processes -2.55598907 3 More
GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA GO Biological Processes -5.19429515 5 More
GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA GO Biological Processes -4.31351457 5 More
GO:1903829 positive regulation of protein localization GO Biological Processes -12.9651258 57 More
GO:1903900 regulation of viral life cycle GO Biological Processes -3.59662203 16 More
GO:1903959 regulation of anion transmembrane transport GO Biological Processes -6.29956701 6 More
GO:1904035 regulation of epithelial cell apoptotic process GO Biological Processes -21.2824424 33 More
GO:1904375 regulation of protein localization to cell periphery GO Biological Processes -3.14645923 7 More
GO:1904377 positive regulation of protein localization to cell periphery GO Biological Processes -2.16161219 8 More
GO:1904407 positive regulation of nitric oxide metabolic process GO Biological Processes -14.4967625 19 More
GO:1904645 response to amyloid-beta GO Biological Processes -11.2505232 12 More
GO:1904646 cellular response to amyloid-beta GO Biological Processes -6.94782947 8 More
GO:1904705 regulation of vascular associated smooth muscle cell proliferation GO Biological Processes -22.4951686 19 More
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation GO Biological Processes -15.2818318 12 More
GO:1904892 regulation of receptor signaling pathway via STAT GO Biological Processes -12.9980471 24 More
GO:1904894 positive regulation of receptor signaling pathway via STAT GO Biological Processes -11.2917234 16 More
GO:1904951 positive regulation of establishment of protein localization GO Biological Processes -13.0308630 46 More
GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell GO Biological Processes -9.55155535 14 More
GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell GO Biological Processes -8.04419623 7 More
GO:1905330 regulation of morphogenesis of an epithelium GO Biological Processes -7.22524154 15 More
GO:1905475 regulation of protein localization to membrane GO Biological Processes -3.01117711 17 More
GO:1905477 positive regulation of protein localization to membrane GO Biological Processes -1.94173448 10 More
GO:1905952 regulation of lipid localization GO Biological Processes -40.6150331 64 More
GO:1905953 negative regulation of lipid localization GO Biological Processes -25.1573575 31 More
GO:2000027 regulation of animal organ morphogenesis GO Biological Processes -7.86416421 22 More
GO:2000112 regulation of cellular macromolecule biosynthetic process GO Biological Processes -24.0725356 37 More
GO:2000116 regulation of cysteine-type endopeptidase activity GO Biological Processes -14.4496812 41 More
GO:2000117 negative regulation of cysteine-type endopeptidase activity GO Biological Processes -4.79670615 8 More
GO:2000146 negative regulation of cell motility GO Biological Processes -30.256132 37 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
GO:2000181 negative regulation of blood vessel morphogenesis GO Biological Processes -32.6997315 52 More
GO:2000272 negative regulation of signaling receptor activity GO Biological Processes -7.12747015 9 More
GO:2000278 regulation of DNA biosynthetic process GO Biological Processes -3.75179201 8 More
GO:2000351 regulation of endothelial cell apoptotic process GO Biological Processes -18.6276983 25 More
GO:2000377 regulation of reactive oxygen species metabolic process GO Biological Processes -19.1025541 38 More
GO:2001056 positive regulation of cysteine-type endopeptidase activity GO Biological Processes -11.1582582 17 More
GO:2001233 regulation of apoptotic signaling pathway GO Biological Processes -35.8481080 51 More
GO:2001234 negative regulation of apoptotic signaling pathway GO Biological Processes -32.1748782 40 More
GO:2001235 positive regulation of apoptotic signaling pathway GO Biological Processes -13.4065813 30 More
GO:2001236 regulation of extrinsic apoptotic signaling pathway GO Biological Processes -20.7647111 26 More
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway GO Biological Processes -19.1764933 21 More
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway GO Biological Processes -7.00132107 13 More
GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand GO Biological Processes -4.65044629 6 More
KEGG pathways: 53 records
KEGG Description Category LogP Number of genes Detail
hsa01523 Antifolate resistance KEGG Pathway -5.90548425 6 More
hsa04010 MAPK signaling pathway KEGG Pathway -13.6331973 26 More
hsa04060 Cytokine-cytokine receptor interaction KEGG Pathway -61.0014447 66 More
hsa04061 Viral protein interaction with cytokine and cytokine receptor KEGG Pathway -30.3399237 29 More
hsa04064 NF-kappa B signaling pathway KEGG Pathway -10.0294934 14 More
hsa04071 Sphingolipid signaling pathway KEGG Pathway -4.55426967 9 More
hsa04150 mTOR signaling pathway KEGG Pathway -2.57210479 7 More
hsa04210 Apoptosis KEGG Pathway -6.60042966 12 More
hsa04217 Necroptosis KEGG Pathway -8.49909048 15 More
hsa04350 TGF-beta signaling pathway KEGG Pathway -6.45304971 17 More
hsa04380 Osteoclast differentiation KEGG Pathway -7.05199617 21 More
hsa04621 NOD-like receptor signaling pathway KEGG Pathway -7.63493695 15 More
hsa04625 C-type lectin receptor signaling pathway KEGG Pathway -5.36927089 9 More
hsa04640 Hematopoietic cell lineage KEGG Pathway -11.4657972 15 More
hsa04650 Natural killer cell mediated cytotoxicity KEGG Pathway -3.46704202 8 More
hsa04668 TNF signaling pathway KEGG Pathway -16.5384917 20 More
hsa04920 Adipocytokine signaling pathway KEGG Pathway -10.4150431 19 More
hsa04930 Type II diabetes mellitus KEGG Pathway -3.96920305 9 More
hsa04931 Insulin resistance KEGG Pathway -8.40376708 21 More
hsa04932 Non-alcoholic fatty liver disease KEGG Pathway -11.2628136 17 More
hsa04933 AGE-RAGE signaling pathway in diabetic complications KEGG Pathway -25.8646207 26 More
hsa04936 Alcoholic liver disease KEGG Pathway -13.3477535 19 More
hsa05010 Alzheimer disease KEGG Pathway -5.39034067 17 More
hsa05014 Amyotrophic lateral sclerosis KEGG Pathway -1.64954984 10 More
hsa05020 Prion disease KEGG Pathway -2.47073365 10 More
hsa05022 Pathways of neurodegeneration - multiple diseases KEGG Pathway -4.18311884 18 More
hsa05130 Pathogenic Escherichia coli infection KEGG Pathway -9.84822677 18 More
hsa05131 Shigellosis KEGG Pathway -5.26807538 14 More
hsa05132 Salmonella infection KEGG Pathway -7.42305681 17 More
hsa05133 Pertussis KEGG Pathway -13.2270528 15 More
hsa05134 Legionellosis KEGG Pathway -13.8022551 14 More
hsa05135 Yersinia infection KEGG Pathway -7.02427022 12 More
hsa05142 Chagas disease KEGG Pathway -21.3868632 23 More
hsa05143 African trypanosomiasis KEGG Pathway -18.5080428 15 More
hsa05144 Malaria KEGG Pathway -31.5561809 24 More
hsa05145 Toxoplasmosis KEGG Pathway -13.6215025 17 More
hsa05146 Amoebiasis KEGG Pathway -14.8474637 18 More
hsa05152 Tuberculosis KEGG Pathway -14.5221547 22 More
hsa05160 Hepatitis C KEGG Pathway -4.71256920 10 More
hsa05161 Hepatitis B KEGG Pathway -5.78517620 12 More
hsa05163 Human cytomegalovirus infection KEGG Pathway -9.77103740 19 More
hsa05164 Influenza A KEGG Pathway -16.0885267 23 More
hsa05165 Human papillomavirus infection KEGG Pathway -8.63301470 40 More
hsa05166 Human T-cell leukemia virus 1 infection KEGG Pathway -5.08552863 13 More
hsa05168 Herpes simplex virus 1 infection KEGG Pathway -3.99478875 17 More
hsa05170 Human immunodeficiency virus 1 infection KEGG Pathway -2.98955463 9 More
hsa05171 Coronavirus disease - COVID-19 KEGG Pathway -24.8179886 34 More
hsa05205 Proteoglycans in cancer KEGG Pathway -18.5545131 27 More
hsa05323 Rheumatoid arthritis KEGG Pathway -22.3868189 23 More
hsa05410 Hypertrophic cardiomyopathy KEGG Pathway -9.74858067 13 More
hsa05414 Dilated cardiomyopathy KEGG Pathway -7.04373804 18 More
hsa05417 Lipid and atherosclerosis KEGG Pathway -33.3876857 40 More
hsa05418 Fluid shear stress and atherosclerosis KEGG Pathway -23.1665561 27 More
Drug-Gene interaction
view
Related drugs: 68 records
Drug name Interaction type Source PMID View
5,7-dihydroxy-4-methylcoumarin DTC view
abbv-257 TTD view
adalimumab antibodyinhibitor TdgClinicalTrialChemblInteractionsTENDPharmGKBTTD 120440411672063616909270230575461502240926244882128476781805018318713756193654012276047524192118145321451734325022960943150465272212979311752352121900961843884115200343 view
afelimomab inhibitor ChemblInteractions 10829362 view
alteplase NCI 8615653 view
amphotericin b DTC view
atorvastatin PharmGKB 18997459 view
az9773 inhibitor ChemblInteractions view
bcg vaccine NCI 10022737 view
benzo[e]pyrene DTC view
bupivacaine NCI 15781526 view
carbamazepine NCIPharmGKB 1556543211294926 view
carboplatin PharmGKB 31616045 view
cefotaxime NCI 835490710989981 view
celastrol TTD view
certolizumab TTD view
certolizumab pegol inhibitor ChemblInteractions view
cyclosporine PharmGKB 18444945 view
dersalazine TdgClinicalTrial view
didanosine NCI 9430255 view
digoxin DTC view
enbrel TTD view
etanercept inhibitorantibody TdgClinicalTrialChemblInteractionsTENDPharmGKBTTD 167206361690927023057546262448821284767818050183187137561936540122760475241921181734325022960943103758461040551810206649221297931175235212190096103383811843884110357816 view
ethambutol PharmGKB 22151084 view
gemcitabine PharmGKB 31616045 view
gentamicin NCI 14565862 view
glimepiride NCI 14686960 view
golimumab inhibitorantibody TdgClinicalTrialChemblInteractionsTENDTTD 21079302 view
halofuginone NCI 16769768 view
homidium bromide DTC view
hydroxychloroquine NCI 9002011 view
infliximab inhibitor TdgClinicalTrialChemblInteractionsTENDPharmGKBTTD 1672063616909270230575461645602426244882128476781805018318713756193654012276047516052578241921181211015417343250229609431548131815691299156741271580459822129793117523522531125512190096184388411569121717673491156952961764224416622728 view
insulin NCI 161255269287059 view
isoniazid PharmGKB 22151084 view
lactulose NCI 11226652 view
lapachone NCI 10075082 view
lenabasum TTD view
lenalidomide ClearityFoundationClinicalTrialTTD view
lenercept inhibitor ChemblInteractions view
meropenem NCI 8354907 view
methimazole NCI 8491516 view
methylene blue DTC view
midazolam NCI 16406030 view
miltefosine NCI 7883777 view
nafamostat TTD view
nerelimomab inhibitor ChemblInteractions view
omeprazole NCI 16815316 view
onercept inhibitor ChemblInteractions view
ortataxel TTD view
ozoralizumab inhibitor TdgClinicalTrialChemblInteractions view
pegsunercept inhibitor ChemblInteractionsTTD view
pentoxifylline TTD view
pf-04236921 TdgClinicalTrial view
placulumab inhibitor TdgClinicalTrialChemblInteractionsTTD view
propylthiouracil NCI 15119959 view
pyrazinamide PharmGKB 22151084 view
pyridoxine NCI 16277693 view
rabeprazole NCI 16815316 view
remtolumab TTD view
rifampin PharmGKB 22151084 view
risperidone NCI 1556777011545247 view
rutin NCI 12423426 view
soblidotin NCI 11855751 view
sorafenib PharmGKB 22736425 view
spironolactone NCI 16837769 view
stavudine PharmGKB 20887379 view
thalidomide inhibitor TdgClinicalTrialTENDTTD 8755512120466821216738312105857121022941175235212113124 view
vadimezan inducer TALC view
Related studies: 33 records
Molecular factor Omics type Application Objective MI type Reference
TNF transcriptomics adverse events[prognosis (bad)] acute myocardial infarction Akatsu T et al. Clin Sci (Lond). 2003
TNF transcriptomics acute myocardial infarction[diagnosis] acute myocardial infarction Shimoda Y et al. Clin Sci (Lond). 2005
TNF transcriptomics complication[prognosis (bad)] acute myocardial infarction Shimoda Y et al. Clin Sci (Lond). 2005
tumor necrosis factor proteomics myocardial reperfusion[prognosis (good)] acute myocardial infarction Pudil R et al. Acta Medica (Hradec Kralove). 1996
tumor necrosis factor proteomics heart failure[prognosis (bad)] acute myocardial infarction Li D et al. Am Heart J. 1999
tumor necrosis factor proteomics recurrent cardiac events[prognosis (bad)] acute myocardial infarction Ridker PM et al. Circulation. 2000
tumor necrosis factor proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Balbay Y et al. Angiology. 2001
tumor necrosis factor proteomics adverse events[prognosis (bad)] acute myocardial infarction Akatsu T et al. Clin Sci (Lond). 2003
tumor necrosis factor proteomics good predictor death;heart failure[prognosis (bad)] acute myocardial infarction Valgimigli M et al. Circulation. 2005
tumor necrosis factor proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Fahim MR et al. Egypt J Immunol. 2004
tumor necrosis factor proteomics heart failure[prognosis (bad)] acute myocardial infarction Fahim MR et al. Egypt J Immunol. 2004
tumor necrosis factor proteomics collateral circulation[prognosis (good)] acute myocardial infarction Rakhit RD et al. Coron Artery Dis. 2005
tumor necrosis factor proteomics type 2 diabetes mellitus[prognosis (bad)] myocardial infarction Nystrom T et al. Clin Sci (Lond). 2006
tumor necrosis factor proteomics medium predictor cardiovascular adverse events[prognosis (bad)] acute ST elevation myocardial infarction Gonzalvez M et al. Rev Esp Cardiol. 2007
tumor necrosis factor proteomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Suzuki H et al. Eur J Clin Invest. 2008
tumor necrosis factor proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Liao XX et al. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2008
tumor necrosis factor proteomics excellent predictor left ventricular remodeling[prognosis (bad)] acute myocardial infarction Kaya EB et al. Anadolu Kardiyol Derg. 2009
tumor necrosis factor proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Goswami B et al. Clin Chim Acta. 2009
tumor necrosis factor proteomics left ventricular systolic dysfunction[prognosis (bad)] acute ST elevation myocardial infarction Lin XM et al. Chin Med J (Engl). 2010
tumor necrosis factor proteomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Mielczarek-Palacz A et al. Wiad Lek. 2011
tumor necrosis factor proteomics adverse events[prognosis (bad)] acute ST elevation myocardial infarction Kehmeier ES et al. Clin Res Cardiol. 2012
tumor necrosis factor proteomics atorvastatin plus bivalirudin[treatment (pharmacotherapy)] acute myocardial infarction Dong SH et al. Ann Palliat Med. 2020
NM_000594.3:c.-488G>A genomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Antonicelli R et al. Coron Artery Dis. 2005
NM_000594.3:c.-488G>A genomics acute myocardial infarction[diagnosis] acute myocardial infarction Ghaderian SM et al. Mol Biol Rep. 2011
NM_000594.3:c.-488G>A genomics acute myocardial infarction[diagnosis] acute myocardial infarction Zeybek U et al. Mol Biol Rep. 2011
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